Blisters are fluid filled sacs which develop beneath the surface layer of the skin. They are usually caused by friction or extremes of temperature such as a scald or a freeze. There are also some dermatological reasons why some people develop blisters such as infection.

Blisters can be subdivided into categories such as bullae, vesicles, or pustules .

Bullae are large blister sites filled with fluid following excessive skin trauma.

Vesicles are small blisters which often appear in clusters and usually indicate a dermatological problem or infection such as tinea pedis (athletes foot).

Pustules are pus filled blisters which may be associated with specific conditions such as psoriasis / palmoplantar pustulosis.

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